High Sensitivity Diagnostic Tests

Our technology uses an electric field and custom assay chemistry to concentrate target biomarkers at the capture test line. The highly concentrated sample results in lower detection limits and higher clinical sensitivity to aid in patient diagnosis for infectious diseases. Phoresa specializes in the design and development of high sensitivity immunoassays for infection targets.

Relevant Publications

• B. Y. Moghadam, K. T. Connelly, and J. D. Posner. 2014. Two orders of magnitude improvement in detection limit of lateral flow assays using isotachophoresis, Analytical Chemistry. doi.​
• B. Y. Moghadam, K. T. Connelly, and J. D. Posner. 2014. Isotachophoretic Preconcenetration on Paper-Based Microfluidic Devices, Analytical Chemistry. doi.
• M. D. Borysiak, K. Kimura and J. D. Posner. 2015. NAIL: Nucleic Acid detection using Isotachophoresis and Loop-mediated isothermal amplification, Lab on a Chip. doi.
• M. D. Borysiak, M. J. Thompson, J. D. Posner. 2016. Translating Diagnostic Assays from the Laboratory to the Clinic: Analytical and Clinical Metrics for Device Development and Evaluation. Lab on a Chip. doi.
• J. Howick, M. J. Thompson, et al. 2014. Current and future use of point-of-care primary care: an international survey in Australia, Belgium, The Netherlands, the UK and the USA. BMJ. http://bmjopen.bmj.com
• V. Hardy, M. J. Thompson, et al. 2016. Exploring the barriers and facilitators to use point-of-care tests in family medicine clinics in the United States. BMC Family Practice. 10.1186/s12875-016-0549-1